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KMID : 0378019620050100101
New Medical Journal
1962 Volume.5 No. 10 p.101 ~ p.104
Progesterone-like Hormones Norlutin, Delaution, Enovid for Prevention of Fetal Loss


Abstract
1. This study is to give the results of patients previously aborted who were treated with Norlutin, Delalutin, and Enovid.
2. The patients who previously aborted include two groups; one treated with hormones and the other treated without hormones.
3. The control group of 5,507 had a fetal salvage of 87.6%; 10.4% abortions up to 22 week and 2% fetal loss in the last part of pregnancy.
4. The abortion and fetal loss rate increased from 9.3% to 21.6% to 69% to 92% with each additional previous pregnancy loss. The fetal loss in the last 4 months of gestation increased from 1.8% to 2.7% to 6.2% with each additional previous abortion.
5. All three progesterone-like hormones are excellent in preventing abortion. In this study Enovid proves superior in the last half of pregnancy.
6. The fetal salvage is greatly improved in the hormone treated groups, compared to the control group.
7. Complications and side effects were very low in women treated with progesterone-like hormones. One hormone caused transitory masculinizing effect in the mothers and enlargement of the clitoris in two female infants.
8. The results using progesterone-like drugs in previous aborters is sufficiently valuable to warrant its further use.
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